References

Rivera AM, Strauss KW, van Zundert A, Mortier E. The history of peripheral intravenous catheters: how little plastic tubes revolutionized medicine. Acta Anaesthesiol Belg. 2005; 56:(3)271-282

Helm RE, Klausner JD, Klemperer JD, Flint LM, Huang E. Accepted but unacceptable: peripheral IV catheter failure. J Infus Nurs. 2019; 42:(3)151-164 https://doi.org/10.1097/NAN.0000000000000326

Platt V, Osenkarski S. Improving vascular access outcomes and enhancing practice. J Infus Nurs. 2018; 41:(6)375-382 https://doi.org/10.1097/NAN.0000000000000304

Carr PJ, Rippey JC, Budgeon CA, Cooke ML, Higgins N, Rickard CM. Insertion of peripheral intravenous cannulae in the Emergency Department: factors associated with firsttime insertion success. J Vasc Access. 2016; 17:(2)182-190 https://doi.org/10.5301/jva.5000487

Carr PJ, Rippey JCR, Cooke ML From insertion to removal: a multicenter survival analysis of an admitted cohort with peripheral intravenous catheters inserted in the emergency department. Infect Control Hosp Epidemiol. 2018; 39:(10)1216-1221 https://doi.org/10.1017/ice.2018.190

Lv L, Zhang J. The incidence and risk of infusion phlebitis with peripheral intravenous catheters: a metaanalysis. J Vasc Access. 2020; 21:(3)342-349 https://doi.org/10.1177/1129729819877323

Marsh N, Larsen EN, Takashima M Peripheral intravenous catheter failure: a secondary analysis of risks from 11,830 catheters. Int J Nurs Stud. 2021; 124 https://doi.org/10.1016/j.ijnurstu.2021.104095

Marsh N, Webster J, Larsen E, Cooke M, Mihala G, Rickard CM. Observational study of peripheral intravenous catheter outcomes in adult hospitalized patients: a multivariable analysis of peripheral intravenous catheter failure. J Hosp Med. 2018; 13:83-89 https://doi.org/10.12788/jhm.2867

Zhang L, Cao S, Marsh N Infection risks associated with peripheral vascular catheters. J Infect Prev. 2016; 17:(5)207-213 https://doi.org/10.1177/1757177416655472

Blauw M, Foxman B, Wu J, Rey J, Kothari N, Malani AN. Risk factors and outcomes associated with hospital-onset peripheral intravenous catheter-associated Staphylococcus aureus bacteremia. Open Forum Infect Dis. 2019; 6:(4) https://doi.org/10.1093/ofid/ofz111

Mermel LA, Allon M, Bouza E Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis. 2009; 49:(1)1-45 https://doi.org/10.1086/599376

Lim S, Gangoli G, Adams E Increased clinical and economic burden associated with peripheral intravenous catheter-related complications: analysis of a US hospital discharge database. Inquiry. 2019; 56 https://doi.org/10.1177/0046958019875562

Maki DG, Kluger DM, Crnich CJ. The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. Mayo Clin Proc. 2006; 81:(9)1159-1171 https://doi.org/10.4065/81.9.1159

Mermel LA. Short-term peripheral venous catheter-related bloodstream infections: a systematic review. Clin Infect Dis. 2017; 65:(10)1757-1762 https://doi.org/10.1093/cid/cix562

Jamal M, Ahmad W, Andleeb S Bacterial biofilm and associated infections. J Chin Med Assoc. 2018; 81:(1)7-11 https://doi.org/10.1016/j.jcma.2017.07.012

Ryder M. Catheter-related infections: it's all about biofilm. Topics in Advanced Practice Nursing eJournal. 2005; 5:(3)

Safdar N, Maki DG. The pathogenesis of catheter-related bloodstream infection with non-cuffed short-term central venous catheters. Intensive Care Med. 2004; 30:(1)62-67 https://doi.org/10.1007/s00134-003-2045-z

Gilardi E, Piano A, Chellini P Reduction of bacterial colonization at the exit site of peripherally inserted central catheters: a comparison between chlorhexidine-releasing sponge dressings and cyano-acrylate. J Vasc Access. 2021; 22:(4)597-601 https://doi.org/10.1177/1129729820954743

Raad I, Costerton W, Sabharwal U, Sacilowski M, Anaissie E, Bodey GP. Ultrastructural analysis of indwelling vascular catheters: a quantitative relationship between luminal colonization and duration of placement. J Infect Dis. 1993; 168:400-407

Raad I. Intravascular-catheter-related infections. Lancet. 1998; 351:(9106)893-898 https://doi.org/10.1016/S0140-6736(97)10006-X

Mermel LA. What is the predominant source of intravascular catheter infections?. Clin Infect Dis. 2011; 52:(2)211-212 https://doi.org/10.1093/cid/ciq108

Elliott TS, Moss HA, Tebbs SE Novel approach to investigate a source of microbial contamination of central venous catheters. Eur J Clin Microbiol Infect Dis. 1997; 16:(3)210-213 https://doi.org/10.1007/BF01709583

Freeman WJ, Weiss AJ, Heslin KC. Overview of U.S. hospital stays in 2016: variation by geographic region.Rockville, MD: Agency for Healthcare Research and Quality (US); 2018

Byrd AL, Belkaid Y, Segre JA. The human skin microbiome. Nat Rev Microbiol. 2018; 16:(3)143-155 https://doi.org/10.1038/nrmicro.2017.157

Grice EA, Segre JA. The skin microbiome. Nat Rev Microbiol. 2011; 9:(4)244-253 https://doi.org/10.1038/nrmicro2537

2021 infusion therapy standards of practice updates. J Infus Nurs. 2021; 44:(4)189-190 https://doi.org/10.1097/NAN.0000000000000436

O'Grady NP, Alexander M, Burns LA Summary of recommendations: guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis. 2011; 52:(9)1087-1099 https://doi.org/10.1093/cid/cir138

Hendley JO, Ashe KM. Effect of topical antimicrobial treatment on aerobic bacteria in the stratum corneum of human skin. Antimicrob Agents Chemother. 1991; 35:(4)627-631 https://doi.org/10.1128/AAC.35.4.627

Selwyn S, Ellis H. Skin bacteria and skin disinfection reconsidered. Br Med J. 1972; 1:(5793)136-140 https://doi.org/10.1136/bmj.1.5793.136

Choudhury MA, Marsh N, Banu S, Paterson DL, Rickard CM, McMillan DJ. Molecular comparison of bacterial communities on peripheral intravenous catheters and matched skin swabs. PLoS One. 2016; 11:(1) https://doi.org/10.1371/journal.pone.0146354

Choudhury MA, Sidjabat HE, Zowawi HM Skin colonization at peripheral intravenous catheter insertion sites increases the risk of catheter colonization and infection. Am J Infect Control. 2019; 47:(12)1484-1488 https://doi.org/10.1016/j.ajic.2019.06.002

Domingue G, Costerton JW, Brown MR. Bacterial doubling time modulates the effects of opsonisation and available iron upon interactions between Staphylococcus aureus and human neutrophils. FEMS Immunol Med Microbiol. 1996; 16:(3-4)223-228 https://doi.org/10.1111/j.1574-695X.1996.tb00139.x

Eda N, Ito H, Shimizu K, Suzuki S, Lee E, Akama T. A study of bacterial growth on the skin surface after a basketball game. Clin Case Rep Rev. 2015; 1:(11)279-282 https://doi.org/10.15761/CCRR.1000189

Livesley MA, Tebbs SE, Moss HA, Faroqui MH, Lambert PA, Elliott TS. Use of pulsed field gel electrophoresis to determine the source of microbial contamination of central venous catheters. Eur J Clin Microbiol Infect Dis. 1998; 17:(2)108-112 https://doi.org/10.1007/BF01682166

Zhang Li, Keogh S, Rickard CM Reducing the risk of infection associated with vascular access devices through nanotechnology: a perspective. International journal of J Nanomedicine. 2013; 8:4453-4466 https://doi.org/10.2147/IJN.S50312

The potential role of through the needle PIVC insertion in reducing early catheter contamination

27 July 2023
Volume 32 · Issue 14

Abstract

HIGHLIGHTS

Over-the-needle (OTN) PIVC devices are at inherent risk of insertion related skin contamination.

Through-the-needle (TTN) catheter deployment resulted in no measurable contamination in this study.

OTN catheters were 1.67 times more likely to be contaminated than TTN in this study.

Aim:

To compare a traditional over-the-needle peripheral intravenous catheter device to a through-the-needle (TTN) peripheral intravenous catheter device for early bacterial contamination during insertion.

Methods:

Five TTN test devices (OspreyIV 20 g SkyDance Vascular, Inc) and 5 OTN comparative devices (Insyte Autoguard 20 g Becton Dickinson) were aseptically inserted through targeted zones inoculated with 1 mL aliquot suspension of approximately 1 × 10 CFU of Staphylococcus aureus among 3 healthy sheep. Immediately after insertion, each study catheter was surgically removed from the surrounding tissue and cultured for the presence of Staphylococcus aureus inoculum that may have been transferred to the catheter during insertion.

Results:

Final culture results of the 5 test articles found no bacterial colonies. Final culture results of the 5 comparative articles revealed 2 of 5 were contaminated with bacterial colonies. The absolute risk reduction is 40%, or a 40% rate of contamination drops to a 0% rate of contamination when the TTN catheter deployment was used. The risk ratio achieved was 1.67, indicating catheters placed using the OTN deployment were 1.67 times more like to be contaminated than the TTN deployed catheters.

Conclusion:

In this present ovine study, the data revealed that use of a novel TTN approach resulted in less contamination than the more traditional OTN approach. Traditional OTN devices, developed over 70 years ago, are at inherent risk of insertion-related contact contamination. The results of this research, as well as previously published studies, point toward considering physical catheter protection strategies such as TTN devices as a potential alternative to OTN devices.

Medical devices designed to access the vascular system for the purpose of infusion therapy date back as early as the mid-1600s when Christopher Wren, a renowned anatomist at Oxford University, used a quill and a pig's bladder to create the first working intravenous infusion device. Little progress was made in the field until 1818 when Dr Blundell performed the first successful human-to-human transfusion using a what he termed a ‘Gravitator.’ This device was composed of a syringe attached to a tube which was attached to a funnel. The donor would bleed into the funnel and the blood would, via gravity, travel down the tube and into patient. This approach was ‘to be used when all other options were exhausted’ and did not have a very high success rate; however, it proved that infusions into the bloodstream could serve as a viable method for improving patient outcomes. While intravenous infusions increased in frequency of use during the late 1800s and early 1900s, it was not until in 1950 that a quantum leap forward occurred when Dr David Massa, a resident in anesthesiology, fitted a polyvinyl chloride catheter over a steel introducer needle, creating the first catheter that could be directly threaded into a vessel after percutaneous venipuncture with a needle.1 This discovery sparked an instant revolution in healthcare and forever changed the way intravenous infusions were delivered. In the more than 70 years that followed, Massa's over-the-needle (OTN) catheter configuration inspired a multitude of innovative peripheral intravenous catheter (PIVC) devices. Iterative improvements in catheter materials, patient comfort, blood control, and needle stick safety contributed to making catheter OTN PIVCs the primary vehicle for delivering life-saving intravenous infusions to upwards of 90% of hospitalized patients.2

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