References

Andrews KL, Houdek MT, Kiemele LJ Wound management of chronic diabetic foot ulcers. Prosthet Orthot Int. 2015; 39:(1)29-39 https://doi.org/10.1177/0309364614534296

Boulton AJM, Vileikyte L, Ragnarson-Tennvall G, Apelqvist J The global burden of diabetic foot disease. Lancet. 2005; 366:(9498)1719-1724 https://doi.org/10.1016/S0140-6736(05)67698-2

Carro GV, Saurral R, Witman EL Artículo especial-revisión ataque de pie diabético. Descripción fisiopatológica, presentación clínica, tratamiento y evolución. Medicina (B Aires). 2020; 80:523-530

Crawford F, Nicolson DJ, Amanna AE Preventing foot ulceration in diabetes: systematic review and meta-analyses of RCT data. Diabetologia. 2020; 63:(1)49-64 https://doi.org/10.1007/s00125-019-05020-7

Ena J, Carretero-Gomez J, Arevalo-Lorido JC, Sanchez-Ardila C, Zapatero-Gaviria A, Gómez-Huelgas R The association between elevated foot skin temperature and the incidence of diabetic foot ulcers: a metaanalysis. Int J Low Extrem Wounds. 2021; 20:(2)111-118 https://doi.org/10.1177/1534734619897501

Fu XL, Ding H, Miao WW, Mao CX, Zhan MQ, Chen HL Global recurrence rates in diabetic foot ulcers: A systematic review and meta-analysis. Diabetes Metab Res Rev. 2019; 35:(6) https://doi.org/10.1002/dmrr.3160

Graz H, D'Souza VK, Alderson DEC, Graz M Diabetes-related amputations create considerable public health burden in the UK. Diabetes Res Clin Pract. 2018; 135:158-165 https://doi.org/10.1016/j.diabres.2017.10.030

International Working Group on the Diabetic Foot. Practical guidelines on the prevention and management of diabetes-related foot disease. 2023. https//iwgdfguidelines.org/guidelines-2023

International Diabetes Federation. IDF Atlas reports. 2022. https://tinyurl.com/2bxyzjfx

Jeffcoate WJ, Vileikyte L, Boyko EJ, Armstrong DG, Boulton AJM Current challenges and opportunities in the prevention and management of diabetic foot ulcers. Diabetes Care. 2018; 41:(4)645-652 https://doi.org/10.2337/dc17-1836

Lazzarini PA, Jarl G, Gooday C Effectiveness of offloading interventions to heal foot ulcers in persons with diabetes: a systematic review. Diabetes Metab Res Rev. 2020; 36:(S1 Suppl 1) https://doi.org/10.1002/dmrr.3275

Lin C, Liu J, Sun H Risk factors for lower extremity amputation in patients with diabetic foot ulcers: a meta-analysis. PLoS One. 2020; 15:(9) https://doi.org/10.1371/journal.pone.0239236

Mairghani M, Jassim G, Elmusharaf K, Patton D, Eltahir O, Moore Z, Sorensen J Methodological approaches for assessing the cost of diabetic foot ulcers: a systematic literature review. J Wound Care. 2019; 28:(5)261-266 https://doi.org/10.12968/jowc.2019.28.5.261

Martínez Brocca MA, 3rd edn. Sevilla, Spain: Junta de Andalucía, Consejería de Salud; 2018 https://juntadeandalucia.es/export/drupaljda/diabetes_mellitus_2018_18_06_2018.pdf

Martínez Brocca MA, Mayoral Sánchez ESevilla, Spain: Junta de Andalucía, Consejería de Salud; 2016 https://juntadeandalucia.es/export/drupaljda/salud_5af065335c108_pidma3.pdf

Monteiro-Soares M, Vale-Lima J, Martiniano J, Pinheiro-Torres S, Dias V, Boyko EJ A systematic review with meta-analysis of the impact of access and quality of diabetic foot care delivery in preventing lower extremity amputation. J Diabetes Complications. 2021; 35:(4) https://doi.org/10.1016/j.jdiacomp.2020.107837

Moulik PK, Mtonga R, Gill GV Amputation and mortality in new-onset diabetic foot ulcers stratified by etiology. Diabetes Care. 2003; 26:(2)491-494 https://doi.org/10.2337/diacare.26.2.491

Narres M, Kvitkina T, Claessen H Incidence of lower extremity amputations in the diabetic compared with the non-diabetic population: A systematic review. PLoS One. 2017; 12:(8) https://doi.org/10.1371/journal.pone.0182081

Pérez-Panero AJ, Ruiz-Muñoz M, Cuesta-Vargas AI, Gónzalez-Sánchez M Prevention, assessment, diagnosis and management of diabetic foot based on clinical practice guidelines. Medicine (Baltimore). 2019; 98:(35) https://doi.org/10.1097/MD.0000000000016877

Peters EJ, Lipsky BA, Aragón-Sánchez J Interventions in the management of infection in the foot in diabetes: a systematic review. Diabetes Metab Res Rev. 2016; 32:(S1)145-153 https://doi.org/10.1002/dmrr.2706

Prompers L, Schaper N, Apelqvist J Prediction of outcome in individuals with diabetic foot ulcers: focus on the differences between individuals with and without peripheral arterial disease. The EURODIALE Study. Diabetologia. 2008; 51:(5)747-755 https://doi.org/10.1007/s00125-008-0940-0

Restrepo Medrano JC: University of Alicante; 2010 https://gneaupp.info/wp-content/uploads/2014/12/40_pdf.pdf

Schaper NC, van Netten JJ, Apelqvist J, Bus SA, Hinchliffe RJ, Lipsky BA Practical Guidelines on the prevention and management of diabetic foot disease (IWGDF 2019 update). Diabetes Metab Res Rev. 2020; 36:(S1 Suppl 1) https://doi.org/10.1002/dmrr.3266

Sen P, Demirdal T, Emir B Meta-analysis of risk factors for amputation in diabetic foot infections. Diabetes Metab Res Rev. 2019; 35:(7) https://doi.org/10.1002/dmrr.3165

Tchero H, Kangambega P, Lin L Cost of diabetic foot in France, Spain, Italy, Germany and United Kingdom: a systematic review. Ann Endocrinol (Paris). 2018; 79:(2)67-74 https://doi.org/10.1016/j.ando.2017.11.005

van Netten JJ, Price PE, Lavery LA Prevention of foot ulcers in the at-risk patient with diabetes: a systematic review. Diabetes Metab Res Rev. 2016; 32:(Suppl 1)84-98 https://doi.org/10.1002/dmrr.2701

Vas PRJ, Edmonds M, Kavarthapu V The diabetic foot attack: ‘Tis too late to retreat!’. Int J Low Extrem Wounds. 2018; 17:(1)7-13 https://doi.org/10.1177/1534734618755582

Vas P, Rayman G, Dhatariya K Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: a systematic review. Diabetes Metab Res Rev. 2020; 36:(S1 Suppl 1) https://doi.org/10.1002/dmrr.3284

Wrobel JS, Mayfield JA, Reiber GE Geographic variation of lower-extremity major amputation in individuals with and without diabetes in the Medicare population. Diabetes Care. 2001; 24:(5)860-864 https://doi.org/10.2337/diacare.24.5.860

Zhang P, Lu J, Jing Y, Tang S, Zhu D, Bi Y Global epidemiology of diabetic foot ulceration: a systematic review and meta-analysis. Ann Med. 2017; 49:(2)106-116 https://doi.org/10.1080/07853890.2016.1231932

Diabetic foot ulcers: evaluating the role of the specialist advanced practice nurse in complex chronic wounds

13 August 2024
Volume 33 · Issue 15

Abstract

Objectives:

To determine the profile of diabetes patients with neuropathic and neuro-ischaemic lesions who are referred to the advanced practice nurse (APN) in complex chronic wounds; to determine whether a training strategy aimed at primary care nurses and nursing homes that care for patients with diabetic foot disease influences the performance of professionals; and to assess the extent, follow-up and evaluation of diabetic foot disease in patients with neuropathic ulcers and neuro-ischaemic ulcers referred to the specialist APN before and after the training.

Methods:

The characteristics of patients referred to the APN over a period of 6.5 years were analysed, as well as the numbers of amputations and deaths pre- and post-training.

Results:

of the total of 103 patients, 78 were men; across both sexes the average age was 69 years. Fifty patients had neuropathic ulcers and 53 had neuro-ischaemic ulcers, with healing rates of 59%. There were 50 amputations and 37 deaths over the study period.

Conclusion:

Prevention of diabetic foot ulcers depends on having in place a fast, agile, practical clinical pathway between primary care and hospital, with the role of the APN, including the co-ordination of care between primary and secondary settings, being key.

Diabetic foot disease is a severe complication involving deep tissue lesions, and it is associated with current or previously diagnosed diabetes. Among the complications that may manifest are peripheral neuropathy, peripheral artery disease, infection, ulcer(s), neuro‑osteoarthropathy, gangrene and amputation. Foot ulceration is among the most serious complications of diabetes, which can lead to a reduced quality of life and incur financial costs for the person affected. Moreover, it places a considerable burden not only on the person's family, but also on health professionals and services, as well as society in general (Zhang et al, 2017; Fu et al, 2019; International Working Group on the Diabetic Foot (IWGDF), 2023). According to the IWGDF:

‘The vast majority of persons with a diabetes-related foot ulcer will have neuropathy. Peripheral artery disease (PAD), generally caused by atherosclerosis, is present in up to 50% of these patients and is an important risk factor for impaired wound healing, gangrene and lower-extremity amputation. A small percentage of foot ulcers in patients with severe PAD are purely ischaemic … the majority of foot ulcers, however, are either purely neuropathic or neuro-ischaemic ….’

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