References

Brünke J. Evaluation of the chemical tightness of CSTDs. Hospital Pharmacy Europe. 2015; 79:35-37

Gurusamy KS, Best LM, Tanguay C, Lennan E, Korva M, Bussières JF. Closed-system drug-transfer devices plus safe handling of hazardous drugs versus safe handling alone for reducing exposure to infusional hazardous drugs in healthcare staff. Cochrane Database Syst Rev. 2018; 3:(3) https://doi.org/10.1002/14651858

Health and Safety Executive. The control of substances hazardous to health regulations 2002 (as amended). Approved code of practice and guidance. 2002. https://www.hse.gov.uk/pubns/priced/l5.pdf (accessed 26 January 2021)

Health and Safety Executive. Safe handling of cytotoxic drugs in the workplace. 2021. https://tinyurl.com/y3mh8ytk (accessed 26 January 2021)

Marler-Hausen T, Holt C, Headley C, Sessink P. Use of a closed-system drug transfer device reduces contamination with doxorubicin during bolus injection. Br J Nurs. 2020; 29:(10)S15-S21 https://doi.org/10.12968/bjon.2020.29.10.S15

National Institute for Occupational Safety and Health. NIOSH alert. Preventing occupational exposures to antineoplastic and other hazardous drugs in health care settings. 2004. https://www.cdc.gov/niosh/docs/2004-165/pdfs/2004-165.pdf (accessed 26 January 2021)

Guidance on handling of injectable cytotoxic drugs in clinical areas in NHS hospitals in the UK. 2018. https://tinyurl.com/y8hasnzo (accessed 26 January 2021)

US Pharmacopeia. General chapter 800. Hazardous drugs—handling in healthcare settings. 2020. https://tinyurl.com/ya7b8mjj (accessed 26 January 2021)

Vyas N, Turner A, Clark JM, Sewell GJ. Evaluation of a closed-system cytotoxic transfer device in a pharmaceutical isolator. J Oncol Pharm Pract. 2016; 22:(1)10-9 https://doi.org/10.1177/1078155214544993

How can we protect cancer nurses from exposure to hazardous drugs?

25 February 2021
Volume 30 · Issue 4

Abstract

Freelance medical writer Christine Clark (chris@salt.u-net.com) reports on an online meeting held in November 2020 on protecting nursing working in oncology from exposure to hazardous drugs

Meeting Chairman Mark Foulkes (President Elect, UK Oncology Nursing Society, and Consultant and Lead Cancer Nurse, Royal Berkshire NHS Foundation Trust) said that one of the longest-running debates in cancer nursing and systemic anticancer treatment (SACT) delivery is the use of closed systems and whether they improve staff safety significantly or whether personal protective equipment (PPE) alone could achieve the same result.

Alison Simons and Samantha Toland (Senior Lecturers at Birmingham City University) have a special interest in SACT safety and the protection of nurses administering chemotherapy.

Reviewing the risks, Ms Simons said that many of the agents used for SACT are hazardous drugs. They are carcinogenic, teratogenic and mutagenic.

‘The drugs cannot distinguish between a patient who is receiving them for treatment and the health professional who is handling them, so there are potential risks for all of us’, said Ms Simons.

There are risks for staff at every point along the drug pathway, from reconstitution and preparation right through to disposal of waste and spillage. The administration step is of particular interest to nurses. Nurses can be exposed to hazardous drugs through inhalation of drug vapours, ingestion from contaminated cups or snacks on wards and by cutaneous absorption from drug splashes.

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