References

Ahmad AS, Ormiston-Smith N, Sasieni PD. Trends in the lifetime risk of developing cancer in Great Britain: comparison of risk for those born from 1930 to 1960. Br J Cancer. 2015; 112:(5)943-947 https://doi.org/10.1038/bjc.2014.606

Approach to the adult with pancytopenia. 2021. https://tinyurl.com/msxkfbyf (accessed 14 February 2022)

Global burden of haematological malignancies. MDEdge Haematology and Oncology. 2018. https://tinyurl.com/2p82znae (accessed 8 February 2022)

Daniels R, Nutbeam T. ABC of sepsis.Chichester: Wiley-Blackwell; 2010

Hill QA, Newland AC. Fatigue in immune thrombocytopenia. Br J Haematol. 2015; 170:(2)141-149 https://doi.org/10.1111/bjh.13385

Mold JW, Roberts M, Aboshady HM. Prevalence and predictors of night sweats, day sweats, and hot flashes in older primary care patients: an OKPRN study. Ann Fam Med. 2004; 2:(5)391-7 https://doi.org/10.1370/afm.72

Moore D, Sweedman M. Advanced nursing practice in the oncology setting, a case study. Australian Journal of Cancer Nursing. 2004; 5:(2)16-24

National Institute for Health and Care Excellence. Neutropenic sepsis: prevention and management in people with cancer. Clinical guideline CG151. 2012. https://www.nice.org.uk/guidance/cg151 (accessed 8 February 2022)

National Institute for Health and Care Excellence. Deep vein thrombosis. Management. 2020a. https://tinyurl.com/2p95kpby (accessed 8 February 2022)

National Institute for Health and Care Excellence. Venous thromboembolic diseases: diagnosis, management and thrombophilia testing. 2020. NICE guideline NG158. 2020b. https://www.nice.org.uk/guidance/ng158 (accessed 8 February 2022)

National Institute for Health and Care Excellence. Suspected cancer: recognition and referral. NICE guideline NG12. 2021a. https://www.nice.org.uk/guidance/ng12 (accessed 8 February 2022)

National Institute for Health and Care Excellence Bruising. 2021b. https://tinyurl.com/3xbexya6 (accessed 8 February 2022)

Peterson MC, Holbrook JH, Von Hales D, Smith NL, Staker LV. Contributions of the history, physical examination, and laboratory investigation in making medical diagnoses. West J Med. 1992; 156:(2)163-165

Public Health England. Guidance. COVID-19 vaccination and blood clotting. 2021. https://tinyurl.com/mr2x972u (accessed 14 February 2021)

Snyder R. Leukemia and benzene. Int J Environ Res Public Health. 2012; 9:(8)2875-2893 https://doi.org/10.3390/ijerph9082875

Sud A, Chattopadhyay S, Thomsen H Analysis of 153 115 patients with hematological malignancies refines the spectrum of familial risk. Blood. 2019; 134:(12)960-969 https://doi.org/10.1182/blood.2019001362

History taking in patients with suspected haematological disease

24 February 2022
Volume 31 · Issue 4

Abstract

This is the first article in a two-part series. The fundamental skill of advanced nursing practice is the ability to undertake concise history taking and examinations to aid differential diagnosis and appropriate referral to specialist services. This article aims to discuss and highlight specific consultation questions and required clinical assessments of a patient with a potential haematological diagnosis. The complexity of a haematological diagnosis may be become clear with the exploration of constitutional symptoms, which include fever, drenching night sweats, loss of appetite or weight. The rapidity of onset of symptoms is pivotal to diagnosis and may influence speed of referral, if required, to specialist haematology teams. Physical symptoms may include shortness of breath, easy bruising, fatigue or palpable enlarged lymph glands. The relevance of these symptoms and what consitutes a haematological emergency will be explored. This article will discuss clinical findings pertinent to haematological diseases, when it is appropriate to refer to specialist haematological services and current national guidance. The second article in this series will examine how critical thinking aids in the diagnosis of blood disorders.

The evolution of advanced nursing practice has been influenced by changes in healthcare delivery, financial constraints and consumer demand. Moore and Sweedman (2004) suggested that the advanced practice role has evolved in response to the development of more complex therapies, limited resources and nursing shortages. Core characteristics of advanced practice include that the practitioner should be clinically autonomous, have a client-centred role and be empowered to make high-level decisions. Many of these decisions become more complex due to the increasing complexity of disease, with malignancies now affecting 1 in 2 of the population and an ageing population (Ahmad et al, 2015).

With increasing access to laboratory tests, diagnostic imaging and other investigations, we should not forget the fundamental importance of history taking and evaluation of patients. In one study of an evaluation of 80 patients, history-taking alone led to the correct final diagnosis in 76% of patients (Peterson et al, 1992).

Register now to continue reading

Thank you for visiting British Journal of Nursing and reading some of our peer-reviewed resources for nurses. To read more, please register today. You’ll enjoy the following great benefits:

What's included

  • Limited access to clinical or professional articles

  • Unlimited access to the latest news, blogs and video content