Anagnostou K, Turner PJ. Myths, facts and controversies in the diagnosis and management of anaphylaxis. Arch Dis Child. 2019; 104:(1)83-90

Anaphylaxis Campaign. Anaphylaxis: Facts and Figures. 2019. (accessed 30 September)

British Society for Allergy and Clinical Immunology. Allergy action plans for children. 2018. (accessed 26 September 2019)

Department of Health. Guidance on the use of adrenaline auto-injectors in schools. 2017. (accessed 26 September 2019)

Foong RX, du Toit G, Fox AT. Asthma, food allergy, and how they relate to each other. Front Pediatr. 2017; 5

Grabenhenrich LB, Dölle S, Moneret-Vautrin A Anaphylaxis in children and adolescents: The European Anaphylaxis Registry. J Allergy Clin Immunol. 2016; 137:(4)1128-1137.e1

Institute for Patient and Family Centred Care. Patient- and family-centered care. 2010. (accessed 30 September 2019)

Jevon P. Severe allergic reaction: management of anaphylaxis in hospital. Br J Nurs. 2008; 17:(2)104-108

Lee S, Bellolio MF, Hess EP, Erwin P, Murad MH, Campbell RL. Time of onset and predictors of biphasic anaphylactic reactions: a systematic review and meta-analysis. J Allergy Clin Immunol Pract. 2015; 3:(3)408-416.e2

National Institute for Health and Care Excellence. Food allergy in under 19s: assessment and diagnosis. Clinical guideline CG116. 2011a. (accessed 26 September 2019)

National Institute for Health and Care Excellence. Anaphylaxis: assessment and referral after emergency treatment. Clinical guideline CG134. 2011b. (accessed 26 September 2019)

Royal College of Paediatrics and Child Health. Allergy care pathways for children: anaphylaxis. 2011. (accessed 26 September 2019)

Resuscitation Council (UK). Emergency treatment of anaphylactic reactions: guidelines for healthcare providers. 2012. (accessed 8 4 2019)

Sheikh A, Shehata YA, Brown SG, Simons FE. Adrenaline (epinephrine) for the treatment of anaphylaxis with and without shock. Cochrane Database Syst Rev. 2008; (4)

Shields L, Zhou H, Pratt J, Taylor M, Hunter J, Pascoe E. Family-centred care for hospitalised children aged 0-12 years. Cochrane Database Syst Rev. 2012; 10

Turner PJ, Gowland MH, Sharma V Increase in anaphylaxis-related hospitalizations but no increase in fatalities: an analysis of United Kingdom national anaphylaxis data, 1992-2012. J Allergy Clin Immunol. 2015; 135:(4)956-963.e1

Wang Y, Allen KJ, Suaini NHA, McWilliam V, Peters RL, Koplin JJ. The global incidence and prevalence of anaphylaxis in children in the general population: a systematic review. Allergy. 2019; 74:(6)1063-1080

Webb LM, Lieberman P. Anaphylaxis: a review of 601 cases. Ann Allergy Asthma Immunol. 2006; 97:(1)39-43

Worth A, Regent L, Levy M, Ledford C, East M, Sheikh A. Living with severe allergy: an Anaphylaxis Campaign national survey of young people. Clinical Translational Allergy. 2013; 3:(2)

Anaphylaxis in children and young people

10 October 2019
Volume 28 · Issue 18

Anaphylaxis can be defined as a severe, generalised and multi-organ reaction (Grabenhenrich et al, 2016; Anagnostou and Turner, 2019). It is at the extreme end of the allergic spectrum and significant symptoms include: rapidly developing life-threatening airway, breathing and/or circulation problems (Grabenhenrich et al, 2016; Anaphylaxis Campaign, 2019). Frequently, these symptoms are connected with skin and mucosal changes. (See Box 1 for other common symptoms).

The presentation of signs and symptoms can vary greatly between individuals. There is a vast number of triggers that can cause anaphylaxis although those most commonly identified in Europe include food, drugs and venom (Grabenhenrich et al, 2016). Food is a particularly common trigger for children and young people (National Institute for Health and Care Excellence (NICE), 2011a).

Register now to continue reading

Thank you for visiting British Journal of Nursing and reading some of our peer-reviewed resources for nurses. To read more, please register today. You’ll enjoy the following great benefits:

What's included

  • Limited access to clinical or professional articles

  • Unlimited access to the latest news, blogs and video content