References

Barrett S, King B. A clinical evaluation of 20 patients when using a new absorbent silicone foam wound dressing: Cutimed Siltec B. Wounds UK. 2019; 14:(3)76-81

Bhat S, Mary S, Giri AP, Kulkarni MJ. Advanced glycation end products in diabetic complications. In: Kartha CC, Ramachandran S, Pillai R (eds). : Springer International; 2017

Blome C, Baade K, Debus ES, Price P, Augustin M. The “Wound-QoL”: A short questionnaire measuring quality of life in patients with chronic wounds based on three established disease-specific instruments. Wound Repair Regen. 2014; 22:(4)504-514 https://doi.org/10.1111/wrr.12193

Brambilla R, Aloisi D, Weingard I Successful VLU healing: Implementation of a comprehensive therapy concept (VERUM) in daily practice. EWMA Journal. 2003; 13:(2)19-23

Briggs M, Closs SJ. The prevalence of leg ulcers: a review of the literature. EWMA Journal. 2003; 3:(2)14-20

Conboy LA, Macklin E, Kelley J, Kokkotou E, Lembo A, Kaptchuk T. Which patients improve: Characteristics increasing sensitivity to a supportive patient–practitioner relationship. Soc Sci Med. 2010; 70:(3)479-484 https://doi.org/10.1016/j.socscimed.2009.10.024

Chadwick P, Ousey K. Bacterial-binding dressings in the management of wound healing and infection prevention: a narrative review. J Wound Care. 2019; 28:(6)370-382 https://doi.org/10.12968/jowc.2019.28.6.370

Charles H. Does leg ulcer treatment improve patients' quality of life?. J Wound Care. 2004; 13:(6)209-213 https://doi.org/10.12968/jowc.2004.13.6.26670

Cole-King A, Harding KG. Psychological factors and delayed healing in chronic wounds. Psychosom Med. 2001; 63:(2)216-220 https://doi.org/10.1097/00006842-200103000-00004

Ebrecht M, Hextall J, Kirtley LG, Taylor A, Dyson M, Weinman J. Perceived stress and cortisol levels predict speed of wound healing in healthy male adults. Psychoneuroendocrinology. 2004; 29:(6)798-809 https://doi.org/10.1016/S0306-4530(03)00144-6

Edmonds ME, Foster AVM. Diabetic foot ulcers. BMJ. 2006; 332:(7538)407-410 https://doi.org/10.1136/bmj.332.7538.407

Franks PJ, Barker J, Collier M Management of patients with venous leg ulcer: challenges and current best practice. J. Wound Care. 2016; 25:S1-S67 https://doi.org/10.12968/jowc.2016.25.Sup6.S1

Green J, Jester R, McKinley R, Pooler A. The impact of chronic venous leg ulcers: a systematic review. J Wound Care. 2014; 23:(12)601-612 https://doi.org/10.12968/jowc.2014.23.12.601

Greenfield S, Kaplan SH, Ware JE, Yano EM, Frank HJ. Patients' participation in medical care. Journal of General Internal Medicine. 1988; 3:(5)448-457 https://doi.org/10.1007/BF02595921

Gentili V, Gianesini S, Balboni PG Panbacterial real-time PCR to evaluate bacterial burden in chronic wounds treated with Cutimed Sorbact. Eur J Clin Microbiol Infect Dis. 2012; 31:(7)1523-1529 https://doi.org/10.1007/s10096-011-1473-x

Guo S, DiPietro LA. Factors affecting wound healing. J Dent Res. 2010; 89:(3)219-229 https://doi.org/10.1177/0022034509359125

Jones J, Barr W, Robinson J, Carlisle C. Depression in patients with chronic venous ulceration. Br J Nurs. 2006; 15:S17-S23 https://doi.org/10.12968/bjon.2006.15.Sup2.21237

Kammerlander G, Locher E, Suess-Burghart A An investigation of Cutimed Sorbact as an antimicrobial alternative in wound management. Wounds UK. 2008; 4:(2)10-18

Meaume S, Dompmartin A, Lok C Quality of life in patients with leg ulcers: results from CHALLENGE, a double-blind randomised controlled trial. J Wound Care. 2017; 28:(7)368-379 https://doi.org/10.12968/jowc.2017.26.7.368

Optimising the patient journey. Made easy. 2013. https://tinyurl.com/y3gko97q

Reiber GE. Epidemiology of foot ulcers and amputations in the diabetic foot, 6th Edition. In: Bowker JH, Pfeifer MA (eds). St. Louis: Mosby; 2001

Exudate management. Made easy. 2010. https://www.woundsinternational.com/resources/details/exudate-management-made-easy (accessed 24 February 2021)

Seckam AM. A multicentre, observational evaluation of the product characteristics of two absorbent foam dressings. Br J Nurs. 2019; 28:(12)S10-S17 https://doi.org/10.12968/bjon.2019.28.12.s10

Seckam AM, Mercer J. Older patients' experiences and perceptions of having their wounds treated with medical-grade honey. Br J Nurs. 2018; 27:(15)S22-S29 https://doi.org/10.12968/bjon.2018.27.15.s22

Sommer R, Augustin M, Hampel-Kalthoff C, Blome C. The Wound-QoL questionnaire on quality of life in chronic wounds is highly reliable. Wound Repair Regen. 2017; 25:(4)730-732 https://doi.org/10.1111/wrr.12578

Stanirowski PJ, Kociszewska A, Cendrowski K, Sawicki W. Dialkylcarbamoyl chloride-impregnated dressing for the prevention of surgical site infection in women undergoing cesarean section: a pilot study. Arch Med Sci. 2016a; 5:(5)1036-1042 https://doi.org/10.5114/aoms.2015.47654

Stanirowski PJ, Bizoń M, Cendrowski K, Sawicki W. Randomized controlled trial evaluating dialkylcarbamoyl chloride impregnated dressings for the prevention of surgical site infections in adult women undergoing cesarean section. Surg Infect (Larchmt). 2016b; 17:(4)427-435 https://doi.org/10.1089/sur.2015.223

Upton D, Andrews A. Sleep disruption in patients with chronic leg ulcers. J Wound Care. 2013; 22:(8)389-394

Upton D, Andrews A. The impact of stress at dressing change in burns patients: a review of the literature into pain and itching. Wounds. 2014; 26:(3)77-82

Upton D, South F. The psychological consequences of wounds—a vicious circle that should not be overlooked. Wounds UK. 2011; 7:(4)136-138

Upton D, Hender C, Solowiej K. Mood disorders in patients with acute and chronic wounds: a health professional perspective. J Wound Care. 2012; 21:(1)42-48 https://doi.org/10.12968/jowc.2012.21.1.42

Upton D, Andrews A, Upton P. Venous leg ulcers: what about well-being?. J Wound Care. 2014; 23:(1)14-17 https://doi.org/10.12968/jowc.2014.23.1.14

Vuolo J. Wound care made incredibly easy, UK edn. London: Lippincott Williams & Wilkins; 2009

Principles of best practice. Wound exudate and the role of dressings.London: MEP Ltd; 2007

Wounds International. Optimising wellbeing in people living with a wound: an expert working group review. 2012. https://tinyurl.com/ybjuqjb7 (accessed 24 February 2021)

Wounds UK. Best Practice Statement. Improving holistic assessment of chronic wounds. 2018. https://tinyurl.com/ycejzvrz (accessed 24)

Clinical performance and quality of life impact of an absorbent bacteria-binding foam dressing

11 March 2021
20 min read
Volume 30 · Issue 5

Abstract

The aim of this prospective multicentre observational study was to assess the clinical performance and safety of Cutimed® Siltec® Sorbact® absorbent bacteria-binding foam dressing in wound healing and its impact on patients' quality of life (QoL). The study was conducted under routine clinical conditions in 5 study sites in Germany and Poland. Each patient with a venous leg ulcer (VLU) or a diabetic foot ulcer (DFU) was observed for 28 days (initial visit and close-out visit, as well as 3 control visits). An assessment of QoL of the patient was undertaken before and after the study. Sixty-two patients were included in the statistical analysis. Clinicians rated the following assessment parameters in relation to Cutimed Siltec Sorbact dressings as ‘very good’ to ‘good’: wearing comfort (rated by the patient), application and removal, exudate absorption with or without compression and fluid retention capacity with or without compression and infection management. The use of Cutimed Siltec Sorbact dressing was beneficial in absorbing wound exudate (chi-square=28.45, P value<0.001), reduction of the viscosity of wound exudate (chi-square=25.63, P value<0.001), and there were more intact, less macerated, red and oedematous wound surroundings. There was also a 9% decrease in the number of infected wounds at the close-out visit. Analysis of the Wound-QoL measures demonstrated a reduction in the perception of performance parameters associated with wound infection. It can therefore be deduced that the use of Cutimed Siltec Sorbact was effective in wound management and had positive implications for patients' QoL.

Wound healing is a complex process. Chronic or hard-to-heal wounds are typically defined as wounds that do not heal in an orderly set of stages or within a predicted timeframe (within 3 months) (Vuolo, 2009). There are often underlying medical conditions, such as obesity, diabetes, infection, peripheral vascular disease, malnutrition, vitamin deficiency, advancing age and immobility. Hard-to-heal wounds include arterial leg ulcers (ALUs), venous leg ulcers (VLUs), diabetic foot ulcers (DFUs) and pressure ulcers.

VLUs are the most common type of leg ulcer (Vuolo, 2009), accounting for 70% to 90% of all leg ulcers (Briggs and Closs, 2003). Signs of VLUs include pitting oedema and haemosiderin staining (hyperpigmentation).

Patients with uncontrolled diabetes may have high plasma glucose levels leading to blood vessel and nerve damage (Bhat et al, 2017). The nerve damage and poor circulation observed in diabetic patients may lead to the development of a foot ulcer. It has been suggested that 1 in 7 diabetic patients will develop a foot ulcer in their lifetime (Reiber, 2001) and good diabetic control is essential to prevent ulcers. If an ulcer is present, it is necessary to prevent it from becoming infected because infection can lead to amputation and long-term disability (Edmonds and Foster, 2006). There are many causes attributed to DFUs such as peripheral arterial disease, diabetic neuropathy and other mechanical forces (pressure, friction and shear).

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