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KiteLock 4%: the next generation of CVAD locking solutions

25 January 2024

Product Focus

02 January 2024

Volume 33 · Issue 2

ISSN (print): 0966-0461

ISSN (online): 2052-2819

Abstract

Central venous access devices (CVADs), including peripherally inserted central catheters (PICCs) and cuffed tunnelled catheters, play a crucial role in modern medicine by providing reliable access for medication and treatments directly into the bloodstream. However, these vital medical devices also pose a significant risk of catheter-related bloodstream infections (CRBSIs) alongside associated complications such as thrombosis or catheter occlusion. To mitigate these risks, healthcare providers employ various strategies, including the use of locking solutions in combination with meticulous care and maintenance protocols. KiteLock 4% catheter lock is a solution designed to combat the triple threat of infection, occlusion and biofilm. This locking solution is described as the only locking solution to provide cover for all three complications.

Catheter-related bloodstream infections (CRBSIs) are a serious complication associated with central venous catheters, frequently caused by microbial colonisation at the catheter site or migration of pathogens from distant sources. These infections can lead to life-threatening conditions, including sepsis, endocarditis, and abscess formation. Consequently, CRBSIs create challenges for both patients and healthcare providers. Various strategies have been developed to minimise the occurrence of CRBSIs, including the use of catheter-locking solutions. These solutions act as antimicrobial agents, and some can prevent the thrombus formation that can cause occlusion and/or biofilms to reduce microbial colonisation within the catheter lumen.

According to a study by Lemiech-Mirowska et al (2021), the prevalence of hospital-acquired or nosocomial infections exceeds 25% in developing countries and is up to 15% in developed countries, resulting in the death of approximately 40 000 hospitalised patients worldwide. It is well documented that up to 90% of inpatients have some form of vascular access device placed during the course of their hospital stay (Platt and Osenkarski, 2018). For most patients, this could be the most invasive procedure they would have experienced, so to reduce the risk of associated complications, it is vital that all measures are taken to protect the catheter in order to protect the patient.

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Central venous access devices

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