References

Ahn MH, Park S, Lee HB Suicide in cancer patients within the first year of diagnosis. Psychooncology. 2015; 24:(5)601-607 https://doi.org/10.1002/pon.3705

Allebeck P, Bolund C Suicides and suicide attempts in cancer patients. Psychol Med. 1991; 21:(4)979-984 https://doi.org/10.1017/S0033291700029962

Andersen BL, Goyal NG, Westbrook TD, Bishop B, Carson WE Trajectories of stress, depressive symptoms, and immunity in cancer survivors: diagnosis to 5 years. Clin Cancer Res. 2017; 23:(1)52-61 https://doi.org/10.1158/1078-0432.CCR-16-0574

Antoni MH, Jacobs JM, Bouchard LC Post-surgical depressive symptoms and long-term survival in non-metastatic breast cancer patients at 11-year follow-up. Gen Hosp Psychiatry. 2017; 44:16-21 https://doi.org/10.1016/j.genhosppsych.2016.10.002

Atkins S, Lewin S, Smith H, Engel M, Fretheim A, Volmink J Conducting a meta-ethnography of qualitative literature: lessons learnt. BMC Med Res Methodol. 2008; 8:(1) https://doi.org/10.1186/1471-2288-8-21

Avis NE, Levine BJ, Case LD, Naftalis EZ, Van Zee KJ Trajectories of depressive symptoms following breast cancer diagnosis. Cancer Epidemiol Biomarkers Prev. 2015; 24:(11)1789-1795 https://doi.org/10.1158/1055-9965.EPI-15-0327

Baker A, Cronin K, Conway P, DeSalvo K, Rajkumar R, Press MJ Making the comprehensive shared care plan a reality. NEJM Catalyst. 2016;

Risk factors for depression in breast cancer survivors: an update. 2012. https://psycnet.apa.org/record/2012-11670-009 (accessed 20 September 2022)

Björkenstam C, Edberg A, Ayoubi S, Rosén M Are cancer patients at a higher suicide risk than the general population?. Scand J Public Health. 2005; 33:(3)208-214 https://doi.org/10.1080/14034940410019226

Blanchard P, Garden AS Looking beyond the numbers: highlighting the challenges of population-based studies in cancer research. J Clin Oncol. 2016; 34:(19)2317-2318 https://doi.org/10.1200/JCO.2015.66.0894

Brandão T, Schulz MS, Matos PM Psychological adjustment after breast cancer: a systematic review of longitudinal studies. Psychooncology. 2017; 26:(7)917-926 https://doi.org/10.1002/pon.4230

Cancer Research UK. Cancer incidence statistics. 2019. https://www.cancerresearchuk.org/health-professional/cancer-statistics/incidence (accessed 26 September 2022)

Carreira H, Williams R, Müller M, Harewood R, Stanway S, Bhaskaran K Associations between breast cancer survivorship and adverse mental health outcomes: a systematic review. J Natl Cancer Inst. 2018; 110:(12)1311-1327 https://doi.org/10.1093/jnci/djy177

Choi SB, Lee W, Yoon JH, Won JU, Kim DW Risk factors of suicide attempt among people with suicidal ideation in South Korea: a cross-sectional study. BMC Public Health. 2017a; 17:(1) https://doi.org/10.1186/s12889-017-4491-5

Choi J, Lee M, Ki M Risk factors for feelings of sadness and suicide attempts among cancer survivors in South Korea: findings from nationwide cross-sectional study (KNHANES IV-VI). BMJ Open. 2017; 7:(12) https://doi.org/10.1136/bmjopen-2017-016130

Chou AF, Stewart SL, Wild RC, Bloom JR Social support and survival in young women with breast carcinoma. Psychooncology. 2012b; 21:(2)125-133 https://doi.org/10.1002/pon.1863

Critical Appraisal Skills Programme. CASP checklists. 2022. https://casp-uk.net/casp-tools-checklists (accessed 20 September 2022)

Dixon-Woods M, Sutton A, Shaw R Appraising qualitative research for inclusion in systematic reviews: a quantitative and qualitative comparison of three methods. J Health Serv Res Policy. 2007; 12:(1)42-47 https://doi.org/10.1258/135581907779497486

Djukanovic I, Carlsson J, Årestedt K Is the Hospital Anxiety and Depression Scale (HADS) a valid measure in a general population 65–80 years old? A psychometric evaluation study. Health Qual Life Outcomes. 2017; 15:(1) https://doi.org/10.1186/s12955-017-0759-9

Faller H, Strahl A, Richard M, Niehues C, Meng K Symptoms of depression and anxiety as predictors of physical functioning in breast cancer patients. A prospective study using path analysis. Acta Oncol. 2017; 56:(12)1677-1681 https://doi.org/10.1080/0284186X.2017.1333630

Gaitanidis A, Alevizakos M, Pitiakoudis M, Wiggins D Trends in incidence and associated risk factors of suicide mortality among breast cancer patients. Psychooncology. 2018; 27:(5)1450-1456 https://doi.org/10.1002/pon.4570

Healthcare Improvement Scotland. Review of the Scottish breast screening programme. 2016. https://www.healthcareimprovementscotland.org/our_work/governance_and_assurance/programme_resources/breast_screening_review.aspx (accessed 20 September 2022)

Hopko DR, Funderburk JS, Shorey RC Behavioral activation and problem-solving therapy for depressed breast cancer patients: preliminary support for decreased suicidal ideation. Behav Modif. 2013; 37:(6)747-767 https://doi.org/10.1177/0145445513501512

Information Services Division. A profile of deaths by suicide in Scotland 2009–2015. 2017. https://tinyurl.com/2p8hd32n (accessed 20 September 2022)

Irons C 2014 Depression.Basingstoke: Palgrave MacMillan; 2014

İzci F, İlgün AS, Fındıklı E, Özmen V Psychiatric symptoms and psychosocial problems in patients with breast cancer. J Breast Health. 2016; 12:(3)94-101 https://doi.org/10.5152/tjbh.2016.3041

Edinburgh Napier University transforming care after treatment final wrap up report. 2015. https://www.napier.ac.uk/research-and-innovation/research-search/outputs/transforming-care-after-treatment-programme-evaluation (accessed 20 September 2022)

Kendal WS, Kendal WM Comparative risk factors for accidental and suicidal death in cancer patients. Crisis. 2012; 33:(6)325-334 https://doi.org/10.1027/0227-5910/a000149

Kim H, Kim K, Kim YH Associations between mental illness and cancer: a systematic review and meta-analysis of observational studies. Eur Rev Med Pharmacol Sci. 2022; 26:(14)4997-5007 https://doi.org/10.26355/eurrev_202207_29286

Kim JM, Jang JE, Stewart R Determinants of suicidal ideation in patients with breast cancer. Psychooncology. 2013; 22:(12)2848-2856 https://doi.org/10.1002/pon.3367

Leung J, Hubbard G, Kyle R, McLaughlin D, Mullen R, Atherton I 33. Positive mental health in women living with breast cancer across geographic locations of residence: a data linkage study using the Scottish Health Survey. Eur J Surg Onco. 2015; 41:(6) https://doi.org/10.1016/j.ejso.2015.03.034

Levi F, La Vecchia C, Lucchini F, Negri E, Saxena S, Maulik PK, Saraceno B Trends in mortality from suicide, 1965–99. Acta Psychiatr Scand. 2003; 108:(5)341-349 https://doi.org/10.1034/j.1600-0447.2003.00147.x

Luctkar-Flude M, Aiken A, McColl MA, Tranmer J What do primary care providers think about implementing breast cancer survivorship care?. Curr Oncol. 2018; 25:(3)196-205 https://doi.org/10.3747/co.25.3826

McFarland DC, Shaffer KM, Tiersten A, Holland J Physical symptom burden and its association with distress, anxiety, and depression in breast cancer. Psychosomatics. 2018; 59:(5)464-471 https://doi.org/10.1016/j.psym.2018.01.005

Moher D, Liberati A, Tetzlaff J, Altman DG Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009; 151:(4)264-269 https://doi.org/10.7326/0003-4819-151-4-200908180-00135

Nock MK, Borges G, Bromet EJ, Cha CB, Kessler RC, Lee S Suicide and suicidal behavior. Epidemiol Rev. 2008; 30:(1)133-154 https://doi.org/10.1093/epirev/mxn002

Odle TG Precision medicine in breast cancer. Radiol Technol. 2017; 88:(4)401M-421M

Robinson D, Renshaw C, Okello C, Møller H, Davies EA Suicide in cancer patients in South East England from 1996 to 2005: a population-based study. Br J Cancer. 2009; 101:(1)198-201 https://doi.org/10.1038/sj.bjc.6605110

Robson A, Scrutton F, Wilkinson L, MacLeod F The risk of suicide in cancer patients: a review of the literature. Psychooncology. 2010; 19:(12)1250-1258 https://doi.org/10.1002/pon.1717

Saad AM, Gad MM, Al-Husseini MJ Suicidal death within a year of a cancer diagnosis: a population-based study. Cancer. 2019; 125:(6)972-979 https://doi.org/10.1002/cncr.31876

Schairer C, Brown LM, Chen BE Suicide after breast cancer: an international population-based study of 723,810 women. J Natl Cancer Inst. 2006; 98:(19)1416-1419 https://doi.org/10.1093/jnci/djj377

Scottish Government. Scottish cancer patients experience survey 2015/16. 2016. https://tinyurl.com/4bevf6te (accessed 20 September 2022)

Vyssoki B, Gleiss A, Rockett IR, Hackl M, Leitner B, Sonneck G, Kapusta ND Suicide among 915,303 Austrian cancer patients: who is at risk?. J Affect Disord. 2015; 175:287-291 https://doi.org/10.1016/j.jad.2015.01.028

Walker J, Waters RA, Murray G Better off dead: suicidal thoughts in cancer patients. J Clin Oncol. 2008; 26:(29)4725-4730 https://doi.org/10.1200/JCO.2007.11.8844

Walker J, Hansen CH, Martin P, Symeonides S, Ramessur R, Murray G, Sharpe M Prevalence, associations, and adequacy of treatment of major depression in patients with cancer: a cross-sectional analysis of routinely collected clinical data. Lancet Psychiatry. 2014; 1:(5)343-350 https://doi.org/10.1016/S2215-0366(14)70313-X

Whitlock FA Suicide, cancer and depression. Br J Psychiatry. 1978; 132:(3)269-274 https://doi.org/10.1192/S0007125000283335

World Cancer Research Fund. UK cancer statistics. 2022. https://www.wcrf-uk.org/preventing-cancer/uk-cancer-statistics (accessed 26 September 2022)

World Health Organization. Suicide. 2021. https://www.who.int/news-room/fact-sheets/detail/suicide2018 (accessed 26 September 2022)

World Health Organization. Cancer. 2022a. https://www.who.int/news-room/fact-sheets/detail/cancer (accessed 26 September 2022)

World Health Organization. International Statistical Classification of Diseases and Related Health Problems (ICD). 2022b. https://www.who.int/standards/classifications/classification-of-diseases (accessed 26 September 2022)

Zainal NZ, Nik-Jaafar NR, Baharudin A, Sabki ZA, Ng CG Prevalence of depression in breast cancer survivors: a systematic review of observational studies. Asian Pac J Cancer Prev. 2013; 14:(4)2649-2656 https://doi.org/10.7314/apjcp.2013.14.4.2649

Zaorsky NG, Zhang Y, Tuanquin L, Bluethmann SM, Park HS, Chinchilli VM Suicide among cancer patients. Nat Commun. 2019; 10:(1) https://doi.org/10.1038/s41467-018-08170-1

Zhong BL, Li SH, Lv SY Suicidal ideation among Chinese cancer inpatients of general hospitals: prevalence and correlates. Oncotarget. 2017; 8:(15)25141-25150 https://doi.org/10.18632/oncotarget.15350

Suicide and women living with and beyond a breast cancer diagnosis

13 October 2022
Volume 31 · Issue 18

Abstract

Early diagnosis and intervention, and the use of targeted cancer treatments, have significantly reduced mortality from breast cancer. Emotional distress following a diagnosis of cancer is a normal and anticipated, but it may manifest in some individuals at some point as a level of anxiety or depression that significantly affects quality of life and coping. In extreme cases, these feelings can move from physical symptoms of low energy and an inability to complete basic tasks to despair and hopelessness. Confronting a cancer diagnosis is a life-changing experience, bringing a sense of vulnerability. This may create or precipitate a crisis that threatens to overwhelm a person, resulting in a negative impact on established coping mechanisms. There appears to be a paucity of literature on suicide or suicide attempts by people living with and beyond a cancer diagnosis. A literature search identified 19 papers on suicide and or suicide ideation in patients who had had a cancer diagnosis, which were included in the review. Two clear themes emerged from the literature: that a cancer diagnosis with or without pre-existing mental health comorbidities is a risk factor for suicide; and that there is a significant incidence and prevalence of anxiety and depression in cancer patient populations. The literature identifies multiple variables that impact on prevalence of mental health disorders after a breast cancer diagnosis. Despite this, there appears to be a lack of guidance at national level for screening for mental health comorbidities in patients with a cancer diagnosis.

Cancer accounts for a considerable illness burden globally, with an estimated 9.6 million deaths attributed to it in 2018; this equates to one in six deaths (World Health Organization (WHO), 2022a). In the UK, despite extensive population-based interventions in healthy lifestyle promotion and cancer screening, there are approximately 375 000 new cancer diagnoses every year (Cancer Research UK (CRUK), 2019). The incidence of cancer is higher in the UK than in almost two-thirds of countries in Europe, and the most common cancers include breast with 56 987 new cases, prostate with 55 068 and lung with 48 754 (World Cancer Research Fund, 2022).

With early diagnosis and intervention and the use of targeted cancer treatments, mortality from breast cancer has decreased significantly (Odle, 2017; CRUK, 2019).

The difficulties experienced by individuals following a cancer diagnosis may be physical, emotional, psychosocial or a combination of all three (Irons, 2014; Antoni et al, 2017, Kim et al, 2022). Emotional distress following a diagnosis of cancer is an anticipated, normal behaviour; however, in some individuals, it may manifest at some point through a management episode or patient journey as a level of anxiety or depression that impacts significantly on quality of life and coping.

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